GERD is caused by the irritation of the esophagus by acid from the stomach. It is characterized by burning feeling in the upper abdomen that rises up into the chest. This pain is usually worse after large meals or when lying down flat after eating. Additionally, these symptoms can be caused by mechanical irritation of the esophagus.
From a mechanical perspective, the lower esophageal sphincter is composed of fibers from the right crura of the diaphragm. This portion of the diaphragm attaches to the upper lumbar spinal vertebrae. Other tissues contributing to mechanical tension of this region include the diaphragm, the esophagus, the phrenoesophageal ligament, the lower 2 ribs, and the transversals fascia.